Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Chlorthalidone British Pharmacopoeia (BP) Reference Standard | 77-36-1 | MFCD00036257 |
Chlorthalidone British Pharmacopoeia (BP) Reference Standard | Mol Wt: 338.77 | 77-36-1 | MFCD00036257 |
Selleck Chemical LLC Voriconazole S1442-10mM/1mL
Voriconazole is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent 14-alpha-sterol demethylase-mediated synthesis of ergosterol
Sigma Aldrich Fine Chemicals Biosciences Cefotaxime Related Compound E United States Pharmacopeia (USP) Reference Standard | 66340-33-8 | 15MG
Cefotaxime Related Compound E United States Pharmacopeia (USP) Reference Standard | Mol Wt: 395.41 | 66340-33-8 | 15MG
Apexbio Technology LLC Mesalamine 89-57-6 500mg
Mesalamine (89-57-6) is a small-molecule inhibitor targeting the I B kinase (IKK) signaling pathway It is designed to modulate the inflammatory response thereby regulating the NF- B pathway and the expression of pro-inflammatory mediators Mesalamine exerts its biological activity primarily through inhibition of cytokine-mediated activation of the NF- B pathway Based on these pharmacological properties mesalamine holds research potential in studies of inflammatory signaling cascades autoimmune conditions and related inflammatory disorders
Medchemexpress LLC Lenalidomide | 191732-72-6 | 99.94% | 25 MG
Lenalidomide (CC-5013) is a derivative of Thalidomide that acts as a molecular glue and is an orally active immunomodulator. It functions as a ligand of ubiquitin E3 ligase cereblon (CRBN), leading to the selective ubiquitination and degradation of lymphoid transcription factors IKZF1 and IKZF3 by the CRBN-CRL4 ubiquitin ligase.
- Inhibits growth of mature B-cell lymphomas, including multiple myeloma.
- Induces IL-2 release from T cells.
- Stimulates T cell proliferation, IFN-γ, and IL-2 production.
- Inhibits pro-inflammatory cytokines (TNF-α, IL-1, IL-6, IL-12) and elevates anti-inflammatory cytokine IL-10 from human PBMCs.
- Downregulates IL-6 production and augments myeloma cell apoptosis.
- Functions as a molecular glue between human E3 ubiquitin ligase cereblon and CKIα.
- Induces ubiquitination and degradation of this kinase, killing leukemic cells by p53 activation.
Selleck Chemical LLC Duvelisib (IPI-145) 10mM/1mL 1201438-56-3 INK1197
Duvelisib (IPI-145, INK1197) is a novel and selective PI3K ?/? inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM in cell-free assays, highly selective for PI3K ?/? than other protein kinases. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC AG-1478 (Tyrphostin AG-1478) 5mg 153436-53-4 NSC 693255
AG-1478 (Tyrphostin AG-1478, NSC 693255) is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR. AG-1478 (Tyrphostin AG-1478) inhibits encephalomyocarditis virus (EMCV) and hepatitis c virus (HCV) by targeting phosphatidylinositol 4-kinase III? (PI4KA). *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Pickering Laboratories Inc Artificial Eccrine Perspiration-Sebum Emulsion, Not Stabilized (250 mL/bottle)
Inspired by the ASTM D4265-98 method for staining, the emulsion uses 5% Artificial Sebum in Eccrine Persepiration. Oleic acid and triethanolamine are added as emulsifiers. Prepared without dust/dirt for a more universal application, this emulsion mimics non-exercise induced skin surface film (SSFL). As SSFL, it can be used to test any topical use product or the stability of any article that will come in contact with human sweat. This product requires refrigeration to remain in solution and prevent rancidity.
Medchemexpress LLC Budesonide impurity C | 1040085-99-1 | MFCD29920082 | 98.6% | 430.53 g/mol | C25H34O6 | 10 MG
Budesonide impurity C is a chemical impurity of the corticosteroid budesonide, supplied as a research reference material for analytical characterization, impurity profiling, and analytical method development in laboratory and quality-control workflows.
- Used for impurity profiling and analytical method development.
- Purity 98.6%.
- Molecular formula C25H34O6.
- Molecular weight 430.53 g/mol.
- CAS number 1040085-99-1 for unambiguous identification.
- Available in small research pack sizes (10 mg).
Selleck Chemical LLC Ganciclovir 250mg 82410-32-0 RS-21592, BW-759
Ganciclovir (RS-21592, BW-759) is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 ?M in a cell-free assay. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Nintedanib impurity 5 | 676326-36-6 | C₁₂H₁₁NO₄ | 50 MG
Nintedanib impurity 5 is an impurity of Nintedanib.
- CAS Number: 676326-36-6
- Molecular Formula: C₁₂H₁₁NO₄
- Molecular Weight: 233.22
- Storage: Store at room temperature for 3 years; in solvent -80°C for 2 years; -20°C for 1 year.
Medchemexpress LLC Gemcitabine monophosphate | 116371-67-6 | 100.0% | 343.18 | C9H12F2N3O7P | 5 MG
Gemcitabine monophosphate (gemcitabine 5′-phosphate) is the 5′-phosphate intermediate of gemcitabine supplied as a solid for in vitro research. It is used as an active metabolite/intermediate in biochemical and anti-cancer studies and for formulation research such as nanoparticle delivery. For research use only.
- CAS number: 116371-67-6
- Molecular formula: C9H12F2N3O7P
- Molecular weight: 343.18
- Purity: 99.98% (manufacturer stated)
- Appearance: white to off-white solid
- Solubility: DMSO 200 mg/mL, water 100 mg/mL (both may require ultrasonic)
- Storage: sealed, away from moisture; in solvent -80°C up to 6 months
- Available pack sizes: small mg quantities (e.g., 5 mg) and larger sizes on request
Selleck Chemical LLC Mitotane S1732-1g
Mitotane (NCI-C04933) is an antineoplastic medication used in the treatment of adrenocortical carcinoma
Medchemexpress LLC Indobufen impurity 1 100mg
Indobufen impurity 16 is an impurity of Indobufen (HY-18763)
Medchemexpress LLC N-(2-(2-methoxy-4-(methylsulfonamido)-5-phenoxyphenyl)-2-oxoethyl)acetamide | 149456-97-3 | MFCD14698146 | 1g
Iguratimod impurity 1 is an impurity of Iguratimod (HY-17009)